Evidence-Based Pet Nutrition: Explore our research.
At BLUE, we’re dedicated to providing science driven nutrition that supports optimal pet health. We strive to advance small animal nutrition through validation of our therapeutic diets, exploration of the latest nutritional technology, and unwavering commitment to evidence-based veterinary literature. We invite you to explore how our collaboration with veterinary and nutrition experts is driving advancements in animal health.
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Evaluation of a New Hydrolyzed Salmon-Based Diet in Dogs With Suspected Cutaneous Adverse Food Reaction…
This multi-center, randomized, blinded, crossover study evaluated the effects of feeding BLUE NVD…
Lewis T et al. Evaluation of a new hydrolyzed salmon-based diet in dogs with suspected cutaneous adverse food reaction: a multi-center randomized triple-blinded clinical trial. In Proceedings of the North…
Novel Food With Mixed Soluble Fiber Promotes Quicker Resolution of Acute Diarrhea in Shelter Kittens
This study evaluated the effects of feeding BLUE NVD GI Support feline dry diet, compared with a…
Frantz NZ et al. Novel food with mixed soluble fiber promotes quicker resolution of acute diarrhea in shelter kittens. J Anim Physiol Anim Nutr. 2020; 104:406.
Novel Food With Mixed Soluble Fiber Promotes Quicker Resolution of Acute Diarrhea in Shelter Puppies
This study evaluated the effect of feeding BLUE NVD GI Support canine dry diet, compared with a…
Frantz NZ et al. Novel food with mixed soluble fiber promotes quicker resolution of acute diarrhea in shelter puppies. J Anim Physiol Anim Nutr. 2020; 104:406.
Novel Food With Mixed Soluble Fiber Promotes Improved Stool Scores in Cats With Chronic Diarrhea
This randomized crossover study evaluated the effects of feeding BLUE NVD GI Support feline dry…
Franz NZ et al. Novel food with mixed soluble fiber promotes improved stool scores in cats with chronic diarrhea. J Anim Physiol Anim Nutr. 2020; 104:406.
A Veterinary Gastrointestinal Diet Affects Fecal Characteristics, Metabolites, Bile Acids, and Microbiota Concentrations…
This randomized controlled parallel study evaluated the effects of feeding BLUE NVD GI Support feline…
Belchik SE et al. A Veterinary Gastrointestinal Diet Affects Fecal Characteristics, Metabolites, Bile Acids, and Microbiota Concentrations of Antibiotic-Treated Cats. J Anim Sci. 2023; 101…
A Veterinary Gastrointestinal Low-Fat Diet Affects Fecal Characteristics, Metabolites, Bile Acids, and Microbiota…
This randomized controlled parallel study evaluated the effects of feeding BLUE NVD GI Support Low…
Belchik SE et al. A Veterinary Gastrointestinal Low-Fat Diet Affects Fecal Characteristics, Metabolites, Bile Acids, and Microbiota Concentrations of Antibiotic-Treated Dogs. J Anim Sci. 2023; 101…
Reduced Protein Food With L-Carnitine Maintains Lean Mass and Renal Health in Senior Cats
This study evaluated the effects of feeding BLUE NVD K+M feline dry diet for 6 months on body…
Frantz NZ et al. Reduced protein food with L-carnitine maintains lean mass and renal health in senior cats. In Proceedings AAVN Clinical Nutrition & Research Symposium. Virtual, June 10-11, 2020.
Effect of a Struvite Dissolution Diet in Cats With Naturally Occurring Struvite Urolithiasis
This university clinical study evaluated the success of feeding BLUE NVD W+U feline dry diet in…
Tefft KM et al. Effect of a struvite dissolution diet in cats with naturally occurring struvite urolithiasis. J Fel Med Surg. 2020.
Feeding a High-Fiber, High-Protein Diet Lowers Serum Fructosamine and Delays Insulin Use in Diabetic Cats
This clinical study evaluated the effects of feeding BLUE NVD W+U feline dry diet in client-owned…
Cohn A et al. Feeding a High-Fiber, High-Protein Diet Lowers Serum Fructosamine and Delays Insulin Use in Diabetic Cats. In Proceedings AAVN Clinical Nutrition & Research Symposium. Austin TX, June…
Serum Biomarkers Predict Improved Body Composition in Overweight Dogs Fed a Therapeutic Diet
Three studies evaluated the effects of feeding BLUE NVD W+U canine dry diet for 60 days on serum…
Panasevich M et al. Serum biomarkers predict improved body composition in overweight dogs fed a therapeutic diet. In Proceedings AAVN Clinical Nutrition & Research Symposium. Virtual, June 2-3…
Improved Body Composition Is Linked to Serum Biomarkers in Overweight Cats Fed a Therapeutic Diet
Two studies evaluated the effects of feeding BLUE NVD W+U feline dry diet for 60 days on serum…
Panasevich M et al. Improved body composition is linked to serum biomarkers in overweight cats fed a therapeutic diet. In Proceedings AAVN Clinical Nutrition & Research Symposium. Virtual, June 2-3…
A Moderate Sodium Novel Dry Diet Dissolves Naturally Occurring Struvite Cystoliths in Cats
This prospective, non-blinded study evaluated the efficacy of BLUE NVD W+U feline dry diet in…
Tefft KM et al. A moderate sodium novel dry diet dissolves naturally occurring struvite cystoliths in cats. In Proceedings AAVN Clinical Nutrition & Research Symposium. Virtual, June 10-11, 2020.
Novel Food Containing Antioxidants and Fish Oil Improves Mobility Scores in Arthritic Dogs
This study evaluated the effects of feeding BLUE NVD W+M canine dry diet, compared with a…
Frantz NZ et al. Novel food containing antioxidants and fish oil improves mobility scores in arthritic dogs. In Proceedings AAVN Clinical Nutrition & Research Symposium. Virtual, June 10-11, 2020.
Evaluation of Antioxidant-containing Kibble on Serum Antioxidant Biomarkers in Adult Beagles
This randomized crossover study evaluated oxidative health biomarkers in 30 healthy adult Beagles fed…
Panasevich M et al. Evaluation of Antioxidant-containing Kibble on Serum Antioxidant Biomarkers in Adult Beagles. J Anim Sci. 2022; 100 Supp 3:57-58.
Antioxidant-containing Kibble Supplemented to Adult Cats Elicited Improvements in Antioxidant Outcomes…
This randomized crossover study evaluated oxidative health biomarkers in 30 healthy adult cats fed Blue…
Panasevich M et al. Antioxidant-containing Kibble Supplemented to Adult Cats Elicited Improvements in Antioxidant Outcomes and C-reactive Protein. J Anim Sci. 2022; 100 Supp 3:58.
Dietary Ground Flaxseed Increases Serum Alpha-Linolenic Acid Concentrations in Adult Cats
This study evaluated the effects of feeding a diet with 2.6% added ground flaxseed, compared with…
Panasevich MR et al. Dietary ground flaxseed increases serum alpha-linolenic acid concentrations in adult cats. Animals 2022; 12:2543.
A Probiotic Blend Improves Fecal Quality and Enhances Gut Immunity in Dogs with Chronic Diarrhea
This crossover study in twenty-two adult dogs, half healthy and half with chronic diarrhea, compared a…
Lin CY et al. A Probiotic Blend Improves Fecal Quality and Enhances Gut Immunity in Dogs with Chronic Diarrhea. J Anim Sci. 2023; 101 Supp 3:464-465.
A Premium Dry Dog Food Elicits Gut Health Benefits Compared with a Grocery Dry Dog Food
The objective of this study was to compare the effects of feeding Blue Buffalo and a grocery dog…
Lin CY et al. A Premium Dry Dog Food Elicits Gut Health Benefits Compared with a Grocery Dry Dog Food. J Anim Sci. 2023; 101 Supp 3:465-466.
A Premium Dry Cat Food Enhances Digestibility and Gut Health in Cats Compared with a Grocery Dry Cat Food
The objective of this study was to compare the effects of feeding Blue Buffalo and a basic grocery…
Lin CY et al. A Premium Dry Cat Food Enhances Digestibility and Gut Health in Cats Compared with a Grocery Dry Cat Food. J Anim Sci. 2023; 101 Supp 3:465.
Saccharomyces Cerevisiae Fermentation Product Modulates Blood Cell Counts and Gut Immunity in Healthy Adult Cats
This study aimed to evaluate the effects of Saccharomyces cerevisiae fermentation product…
Lin CY et al. Saccharomyces Cerevisiae Fermentation Product Modulates Blood Cell Counts and Gut Immunity in Healthy Adult Cats. J Anim Sci. 2023; 101 Supp 3:462.
Saccharomyces Cerevisiae Fermentation Product Influences Indicators of Gut Health and Function in Healthy Adult…
This study aimed to evaluate the effects of Saccharomyces cerevisiae fermentation product…
Norton SA et al. Saccharomyces Cerevisiae Fermentation Product Influences Indicators of Gut Health and Function in Healthy Adult Cats. J Anim Sci. 2023; 101 Supp 3:460-461.; 101 Supp 3:460-461.
Saccharomyces Cerevisiae Fermentation Product Promotes Improved Preference and Consumption in Adult Cats Fed an…
The objective of this study was to quantify key indicators of palatability of Saccharomyces…
Norton SA et al. Saccharomyces Cerevisiae Fermentation Product Promotes Improved Preference and Consumption in Adult Cats Fed an Extruded Diet. J Anim Sci. 2023; 101 Supp 3:461-462.
Effects of a Saccharomyces Cerevisiae Fermentation Product-supplemented Diet on Fecal Characteristics, Oxidative…
The objective of this randomized, crossover study was to measure the effects of Saccharomyces…
Yotis SM et al. Effects of a Saccharomyces Cerevisiae Fermentation Product-supplemented Diet on Fecal Characteristics, Oxidative Stress, and Blood Gene Expression of Adult Dogs Undergoing Transport…
Effects of a Saccharomyces Cerevisiae Fermentation Product-supplemented Diet on Circulating Immune Cells and…
The objective of this randomized, crossover study was to measure the effects of Saccharomyces…
Yotis SM et al. Effects of a Saccharomyces Cerevisiae Fermentation Product-supplemented Diet on Circulating Immune Cells and Oxidative Stress Markers of Dogs. J Anim Sci. 2022; 100 Supp 3:276.
Effect of a Yeast Product on Palatability, Fecal Microbiota, and Blood Values of Adult Cats
The objective of this randomized, crossover study was to measure the effects of Saccharomyces…
Lin CY et al. Effect of a Yeast Product on Palatability, Fecal Microbiota, and Blood Values of Adult Cats. J Anim Sci. 2022; 100 Supp 3:51.
Altered Fecal Microbiota, IgA, and Fermentative End-Products in Adult Dogs Fed Prebiotics and a Nonviable…
In this randomized crossover study, the effect of nonviable Lactobacillus acidophilus (NVDL) and a…
Panasevich MR et al. Altered fecal microbiota, IgA, and fermentative end-products in adult dogs fed prebiotics and a nonviable Lactobacillus acidophilus. J Anim Sci. 2021; 99:1-11.
Performance of Sunflower Protein Meal and Dried Yeast As Secondary Protein Sources in Feline Diets
This study aimed to assess various levels of sunflower protein meal and dried yeast on nutrient…
Brewer L et al. Performance of sunflower protein meal and dried yeast as secondary protein sources in feline diets. J Anim Sci. 2021; 99 Supp 3:334-335.
Performance of Sunflower Protein Meal and Dried Yeast As Secondary Protein Sources in Canine Diets
This study aimed to assess various levels of sunflower protein meal (SPM) and dried yeast (DY)…
Brewer L et al. Performance of sunflower protein meal and dried yeast as secondary protein sources in canine diets. J Anim Sci. 2021; 99 Supp 3:335.
Inclusion of Lemna as a Plant-Based Protein Ingredient in Dog and Cat Diets
In this study, diets containing Lemna, a novel plan-based protein, at varying inclusion levels, were…
Panasevich M et al. Inclusion of Lemna as a plant-based protein ingredient in dog and cat diets. J Anim Sci. 2021; 98 Supp 4:317.
Nonviable Lactobacillus Acidophilus Consumption Decreases Digestibility but Improves Dysbiosis Index in Cats with…
In this randomized crossover study, healthy adult cats were fed both a control dry kibble diet with…
Lin CY et al. Nonviable Lactobacillus Acidophilus Consumption Decreases Digestibility but Improves Dysbiosis Index in Cats with Chronic Diarrhea. In Proceedings AAVN Clinical Nutrition &…
Including a Nonviable Lactobacillus Acidophilus Increases Digestibility in Healthy Dogs and Dogs with Chronic…
In this randomized crossover study, a mix of healthy adult dogs and adult dogs with chronic diarrhea…
Lin CY et al. Including a Nonviable Lactobacillus Acidophilus Increases Digestibility in Healthy Dogs and Dogs with Chronic Diarrhea. In Proceedings AAVN Clinical Nutrition & Research Symposium…
Effects of Dietary Potassium Fortification on Potassium Efflux and Serum Level in Healthy Adult Cats
In this randomized crossover study, the effect of dietary potassium fortification was evaluated in…
Mitsuhashi Y et al. Effects of Dietary Potassium Fortification on Potassium Efflux and Serum Level in Healthy Adult Cats. In Proceedings AAVN Clinical Nutrition & Research Symposium. Austin…
Effects of a Saccharomyces Cerevisiae Fermentation Product-Supplemented Diet on Skin and Coat Health of Dogs
The objective of this randomized, crossover study was to measure the effects of Saccharomyces…
Yotis SM et al. Effects of a Saccharomyces Cerevisiae Fermentation Product-Supplemented Diet on Skin and Coat Health of Dogs. In Proceedings AAVN Clinical Nutrition & Research Symposium. Austin…
Prebiotics Plus Novel Bacterial-Derived Prebiotic Shift Fecal Microbiota, Metabolites, and IgA in Healthy Adult…
In this randomized crossover study, the effect of a novel bacterial-derived prebiotic and mixed…
Panasevich M et al. Prebiotics plus novel bacterial-derived prebiotic shift fecal microbiota, metabolites, and IgA in healthy adult dogs. In Program Global Animal Nutrition Summit. University of Guelph…
“I have become a huge advocate of BLUE Natural Veterinary Diet™. The efficacy and palatability of the ingredients and formulation of the diet have aided in my treatment protocols. More importantly, pet owners have come to trust in the BLUE brand.”
Dr. Daniel Choi, DVM, MBA from Graceful Animal Hospital, Rancho Cucamonga, CA
“I am happy with the palatability, digestibility testing, and technology, of BLUE Natural Veterinary Diet™. I am especially pleased to hear our clients say their pets were picky and now LOVE to eat. I feel confident using BLUE NVD in my patients, so much so I use them in my own pets.”
Ashley Detwiler, DVM, DACVD from Pittsburgh Veterinary Dermatology
“BLUE Natural Veterinary Diet™ offers unique combinations of features and benefits that work well for patient management. Blue Buffalo is a company that I have come to trust and rely on over the years and what I most appreciate is their support and transparency. They are a welcome addition to the landscape of veterinary therapeutic diets.”
Donna M. Raditic DVM, ACVIM (Nutrition), Board Certified Veterinary Nutritionist® from Nutrition and Integrative Medicine Consultants
“I highly recommend the HF diet: pets love it, and it has proven to be an excellent tool for managing food allergies in both dogs and cats. I've been impressed with the very positive results in skin health and overall happiness of my food-allergic patients.”
Carine Laporte, VMD, DACVD from Dermatology for Animals, Salt Lake City, UT
